Vitamin D with K- I recommend 5,000 IU a day in dark, winter months
“Vitamin D plays a critical role in regulating the immune system. VDRs (vitamin D receptors) are expressed on B cells, T cells, and antigen-presenting cells, which are immunologic cells that control innate and adaptive immune responses.” 1
“Up to 70% of adult whites and 95% of adult African Americans in the US have a vitamin D level under 30 ng/mL.” 2 I like to see vitamin D3 levels around 80 ng/mL, or at least 60 ng/mL.
Multivitamin with methylated Bs- one serving a day
Here are a few ways a multivitamin will support your immune system:
- B6, B12, and folate all support immunity in the gut, and we know that COVID can survive the stomach and attack the gut lining. 3,4
- Vitamin A promotes intestinal immune response and provides immunoregulation by regulating membrane fluidity and gap-junctional communication and enhances burst activity of phagocytes(I like that phrase), amongst other functions. 3
- Selenium supports antioxidant response, positively affecting leukocytes and natural killer cells. 3
Omega 3s- 1.5 gm a day, split between EPA and DHA
Fish oil strengthens your cellular membranes and has multiple benefits beyond immunity, including fortifying the brain and gut barriers. 5
“Ten volunteers were given fish oil supplementation containing 26% EPA and 54% DHA daily for two months. Thereafter, the phagocytic capacity of the neutrophils in the blood was increased with 62%.” 6
Probiotic- I recommend working up to 2 MegaSporeBiotic a day
“Different Bacillus strains have been reported to display antimicrobial, anti-oxidative and immune-modulatory activity in the host….the antagonistic activity of Bacillus spp. has been explored against a large number of pathogens.” 7
Probiotics have anti-inflammatory properties related to the stimulation of secretory IgA synthesis in mucous membranes and the production of cytokines.” 8
Here’s some very interesting findings on one probiotic strain, Bacillus clausii:
“Bacillus clausii is an aerobic, spore-forming bacterium that is able to survive transit through the acidic environment of the stomach and colonize the intestine even in the presence of antibiotics.
B. clausii may exert a significant and persistent impact on RI (respiratory infections) in children and is safe and well-tolerated.” 8